combination chemotherapy

MSC, a new benzoquinone-containing natural product with antimetastatic effect


Authors
Journal
Cancer Biotherapy and Radiopharmaceuticals
Release date
1999; 14(4):277-89.
Abstract/summary

An orally applicable fermentation product of wheat germ containing 0.04% substituted benzoquinone (MSC) has been invented by Hungarian chemists under the trade name of AVEMAR. Oral administration (3 g/kg body weight) of MSC enhances blastic transformation of splenic lymphocytes in mice. The same treatment shortens the survival time of skin grafts in a co-isogenic mouse skin transplantation model, pointing to the immune-reconstructive effect of MSC. A highly significant antimetastatic effect of MSC has been observed in three metastasis models (3LL-HH, B16, HCR-25).

Keywords
Content type
Pubmed
Original publication
Professional work place of the authors