anti-inflammatory effect
Fermented wheat germ extract (avemar) inhibits adjuvant arthritis
Authors
Journal
Annals of the New York Academy of Sciences
Release date
2007; 1110:384-361.
Abstract/summary
Anti-inflammatory efficacy of the fermented wheat germ extract (FWGE, Avemar) in the rat adjuvant arthritis (AA) model was examined. To Wistar rats with AA, different doses of FWGE and anti-inflammatory drugs (indomethacin, dexamethasone) as monotherapies were administered and FWGE and either diclofenac or dexamethasone were also given in combination. Besides plethysmographies of the paws, histological investigations of synovial tissues were also performed along with detection of CD4+ and CD8+ T lymphocytes.
Keywords
Content type
Pubmed
Original publication
Professional work place of the authors
- 1st Institute of Pathology and Experimental Cancer Research, Semmelweis University Budapest, Hungary
- Department of Medicine 'B', Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel
- Department of Medicine C, Sheba Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Hashomer, Israel
- Department of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, Szeged, Hungary
- Jewish University, Budapest, Hungary
- National Institute of Oncology, Budapest, Hungary
- National Institute of Rheumatology and Physiotherapy, Budapest, Hungary
