Ion G
Fermented wheat germ extract induces apoptosis and downregulation of major histocompatibility complex class I proteins in tumor T and B cell lines
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The fermented wheat germ extract (code name: MSC, trade name: Avemar), with standardized benzoquinone content has been shown to inhibit tumor propagation and metastases formation in vivo. The aim of this study was to understand the molecular and cellular mechanisms of the anti-tumor effect of MSC. Therefore, we have designed in vitro model experiments using T and B tumor lymphocytic cell lines.
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Professional work place of the authors
- Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary
- Central Food Research Institute, Budapest, Hungary
- Department of Biochemistry and Food Technology, Budapest Universty of Technology and Economics , Budapest, Hungary
- Department of Medicine 'B', Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel
- Lymphocyte Signal Transduction Laboratory, Institute of Genetics and Cytokine Group, Institute of Biochemistry, Szeged, Hungary
- National Institute of Oncology, Budapest, Hungary






