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Frequently asked questions
- Who should take AVEMAR?
- What are the benefits of AVEMAR?
- Can it be taken during radiotherapy or chemotherapy?
- What are the advantages of the AVEMAR supportive therapy?
- What are the main components of AVEMAR's mode of action?
- Where is AVEMAR's place in oncotherapy?
- Based on clinical experience, which type of cancers have the best response rate to AVEMAR treatment?
- How should the product be administered?
- Can the product be dissolved in anything other than water?
- Should it be used continuously or as part of a course of treatment?
- When should treatment start?
- Is it normal for the product to have an unpleasant taste?
- How should AVEMAR be stored?
- How long can AVEMAR be kept at room temperature before it loses its potency and what decompositional processes can set in?
- Can supplementary products be taken while using AVEMAR?
- How long can I continue taking AVEMAR?
- What are its side effects?
- Are there any conditions in which Avemar should not be used and, if so, what are these conditions?
- Why should the product be avoided after trans-plantations?
- If a patient who has been taking AVEMAR is about to have a bone marrow transplantation, can he continue with the product after the transplant-ation?
- Are you aware of any interactions between Avemar and other drugs?
- What are the potential results of an overdose?
- Can the product be taken by diabetics?
- Is the product recommended for children?
- Can patients with impaired liver and kidney function take AVEMAR?
- Can the consumption of wheat germ replace the AVEMAR treatment?
- Is AVEMAR registered in countries other than Hungary?
- Who should take AVEMAR?
Those suffering from solid tumors and malignant hemato-logical diseases, regardless of the stage of the disease.
- What are the benefits of AVEMAR?
- increases life expectancy
- delays or permanently stops the progression of malignant diseases
- shortens the post-operative period
- Can it be taken during radiotherapy or chemotherapy?
Its use alongside these treatments is strongly recommended, since it reduces their side effects and, at the same time, syn-ergistically enhances the effectiveness of the oncotherapy
- What are the advantages of the AVEMAR supportive therapy?
Experiments have shown that it has a multiple effect on the immune system and that it is not an immunostimulant, having rather a modulating/integrating effect - that is, it restores impaired immune functions, but also corrects those immune reactions which are pathologically over-stimulated.
It significantly delays or prevents local recurrence and metastasis in lymph nodes or in distant organs.
It synergistically enhances the anti-tumor effects of chemo-therapeutic agents while significantly alleviating the harmful hematological and general toxic effects of chemotherapy and radiotherapy.
It significantly enhances the therapeutic effects of estrogen-antagonists in estrogen- receptor positive breast cancer.
It enhances the patient's physical performance.
It improves the patient's quality of life.
It has a beneficial influence on the patient's general health state.
Most cancer patients gain weight.
The product is of natural origin.
It is certified not to have any adverse side effects.
- What are the main components of AVEMAR's mode of action?
Inhibition of malignant proliferation, anti-metastatic effects
Immunological effects
Chemopreventive effects
Metabolic effects
- Where is AVEMAR's place in oncotherapy?
Avemar is not a chemoterapeutic agent, but a supportive product that is non-toxic and possesses a number of specific advantages.
Oncotherapy performed in parallel with Avemar is proven to be more effective in most cases than onco-logical therapy on its own.
It can be administered in cases when active oncotherapy is no longer an option.
Avemar treatment cannot be regarded as an alternative therapy, nor is it a cancer treatment method of unproven effect.
- Based on clinical experience, which type of cancers have the best response rate to AVEMAR treatment?
As is indicated in the instructions accompanying Avemar, its known beneficial effects and lack of toxic side effects renders the application of Avemar both possible and permissable for all types of tumors. Naturally, we have the most experience with diseases in which Avemar was used in the frame of clinical trials, namely gastrointestinal cancers (especially colorectal cancer), squamous cell carcinoma of the oral cavity and malignant melanomas. We also have somewhat less, but nevertheless sufficient, evidence regarding the treatment of bladder and renal cancer, cancer of the pharynx/larynx, cancer of the salivary glands, liver cancer and breast cancer for those cases where objective methods could be used to establish the Avemar's effectiveness. Never-theless, it is important to emphasize that we never replaced standard therapies with Avemar, the therapy was always left unchanged and Avemar was used only as supplementary treatment. This must be taken into account when considering reports on its anti-tumor efficiency; however, it is also true that Avemar noticeably improves the anti-tumor effects of stand-ard anticancer procedures.
- How should the product be administered?
Patients of average weight (70 kg or less) should put one spoonful (9 g) of Avemar into a glass using the measuring spoon provided with the product, add approximately 150 ml of cold water and mix thoroughly before drinking. The dissolving of the granules can be helped by shaking the mixture in a closed container. It is important to note that, in solution, Avemar is unstable. Fresh Avemar solution should be used within 30 minutes of preparation. Patients with a body weight of 90 kg or more should consume two 9 g doses of Avemar per day.
- Can the product be dissolved in anything other than water?
It is recommended to dissolve the product in cold water. If this form of ingestion poses a problem for the patient, the product can be dissolved in non-carbonated soft drinks, cold tea or cocoa, or even in a soft yogurt or kefir.
- Should it be used continuously or as part of a course of treatment?
Avemar should be used continuously and without interruption until the disease is cured.
- When should treatment start?
Ideally, treatment with Avemar should start right after the diagnosis is made and can be taken before any other active therapy (surgery, chemotherapy, radiotherapy) takes place.
- Is it normal for the product to have an unpleasant taste?
Unfortunately, yes. No artificial compounds are used during production. The unpleasant taste of the product is moderated by the use of flavourings and is due to the fermentation process. If the patient is absolutely unable to take the product because of its taste, the granules can, exceptionally, be re-placed by capsules. In this case, the patient should be provided with some form of liquid for simultaneous ingestion.
- How should AVEMAR be stored?
Keep it stored in a sealed container between 5-15°C (pre-ferably in a refrigerator). After opening, Avemar can be used for up to 2 months (taking care to note its expiration date).
- How long can AVEMAR be kept at room temperature before it loses its potency and what decompositional processes can set in?
As explained in the instructions, Avemar should be kept between 5-15°C, preferably in the refrigerator. No harm will come to the product should it be accidentally left at room temperature for a few days. However, exposure to temperatures above 30°C for even as few as 24 hours will damage Avemar.
- Can supplementary products be taken while using AVEMAR?
Yes, vitamins and multivitamins, as well as various dietary supplements and medicinal preparations can be taken.
- How long can I continue taking AVEMAR?
As far as we know, Avemar can be taken for an unlimited period of time or, at least, for as long as it continues to have positive effects - in the case of cancer patients, until the disease is cured. The decision to begin treatment, as well as its mo-nitoring and completion, is the responsibility of the attending physician, though, in certain cases, the decision to stop treat-ment should be taken by both the patient and physician.
- What are its side effects?
Clinical results up to this time suggest that no serious side effects should be expected. Soft stool, unsettled stomach and nausea (primarily because of the taste) are infrequent side effects caused by Avemar. It is quite common for patients to see certain complaints caused by the disease itself as side effects of Avemar. The weight gain experienced by most patients after using the product is not a side effect, but one of its most important natural effects.
- Are there any conditions in which Avemar should not be used and, if so, what are these conditions?
There are some such cases, and they are listed in the in-structions given on the side of the product packaging.
The most significant contraindications are the followings:
- Transplantation (except in cases where the patient's own tissue is being transplanted)
- Celiac disease
- Hereditary fructose intolerance
- Pregnancy and lactation
- Why should the product be avoided after trans-plantations?
Because of its immunomodulant effect.
- If a patient who has been taking AVEMAR is about to have a bone marrow transplantation, can he continue with the product after the transplant-ation?
Unfortunately not, as Avemar can enhance the rejection disposition of any transplanted tissue, including that used in bone marrow heterotransplants. Exceptions can only be made in the case of autotransplants or bone marrow derived from an identical twin.
- Are you aware of any interactions between Avemar and other drugs?
None are known, except that with vitamin C, which may weaken the potency of Avemar when taken simultaneously. As a result, Avemar and vitamin C should not be taken within two hours of one another.
- What are the potential results of an overdose?
An overdose should have no consequences. The product has no toxic dose.
- Can the product be taken by diabetics?
Yes.
- Is the product recommended for children?
Not at the moment, but will be shortly.
- Can patients with impaired liver and kidney function take AVEMAR?
These are not included on the list of contraindications, as potenital accumulation cannot raise plasma concentration to such levels that it would result in toxic effects. In such cases however, side effects should be monitored more closely.
- Can the consumption of wheat germ replace the AVEMAR treatment?
Not at all. The chemical properties of wheat germ's com-ponents are profoundly altered during the production pro-cesses of Avemar. Therefore, even though they may share a common background, the chemical composition and effect of Avemar belong to entirely different categories.
- Is AVEMAR registered in countries other than Hungary?
Yes, in the Czech Republic and Bulgaria, with the same indications as in Hungary. Avemar is also available in 10 other countries, with registration pending in several others.
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